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On 25 March 2025, Botswana's Ministry of Health reported a significant increase in malaria cases, related to recent heavy rains. This outbreak, which began in Okavango, has spread to several other districts including Boteti, Chobe, Ghanzi, Ngami and Tutume. There have also been reports of cases in non-endemic areas, including Francistown, Gaborone, Mahalapye and Serowe.
Until further notice, for all travellers to the districts mentioned above, antimalarial chemoprophylaxis may be considered as per the advice below.
All travellers to Botswana should:
Antimalarial chemoprophylaxis is advised for all travellers to northern Botswana; atovaquone-proguanil or doxycycline or mefloquine is recommended.
Until further notice, antimalarial chemoprophylaxis (atovaquone-proguanil or doxycycline or mefloquine) may be considered for all travellers to the districts mentioned above.
Anyone travelling to Botswana should be vigilant for the signs of malaria during, and on return from, travel and seek immediate medical attention if they have a fever or flu-like illness.
See the TRAVAX Malaria section and Botswana country page for further information.
