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Yellow Fever, Green Book Chapter and Pre-vaccination Checklist Update

14 March 2024

The UK Health Security Agency recently published updated guidance on yellow fever (YF) vaccination in the Ggreen Book (Immunisation against infectious disease: Yellow fever. Chapter 35). The most recent update (March 2024) relates to clarification on reinforcing yellow fever vaccine doses for the small subset of individuals at continued risk of yellow fever and who might not have developed long term protection from their initial YF vaccination.

Following the recent updates to the YF chapter, the NaTHNaC/PHS YF pre-vaccination checklist has been reviewed with minor updates to reflect the changes within the YF chapter.

Advice for health professionals

Health professionals are reminded that as part of the pre-travel risk assessment and for patient safety, all healthcare professionals working in YFVCs should complete a YF pre-vaccination checklist with the traveller to help the healthcare professional risk assess a person's suitability for YF vaccine.

Instructions on how to download and use the YF pre-vaccination checklist can be found here:

Healthcare professionals that have downloaded and/or printed for use a previous version of the pre-vaccination checklist, should replace it with the version dated February 2024.

The NaTHNaC/PHS YF pre-vaccination checklist is a tool designed to:

  • help the healthcare professional risk assess a person’s suitability for YF vaccination
    • it does not replace the broader individual risk assessment in the travel health consultation
  • be completed by the person travelling in advance of, or during, the consultation
    • but must be carefully reviewed by the advising healthcare professional as part of a shared decision-making process for YF vaccination

Health care professionals should always discuss the risk of YF disease and the potential risk of vaccination fully with patients to enable them to make an informed decision regarding proceeding with YF vaccination.

For more information on YF vaccine, serious adverse events and information on contraindications to YF vaccination, please see the following pages on TRAVAX.

For specific information on YF disease risk and ICVP requirements in individual countries, please go to the individual Country Information pages.

Health professionals must refer to Yellow fever: the green book, chapter 35 for current guidance on the administration of YF vaccine in the United Kingdom. This includes the use of a YF pre-vaccination checklist. Advice in the green book may differ from that in vaccine manufacturers’ Summary of Product Characteristics (SmPC); when this occurs, the recommendations in the green book (which are based on current expert advice received from the Joint Committee on Vaccination and Immunisation (JCVI)) should be followed.

If a healthcare professional has any concerns about a traveller’s suitability for receiving YF vaccine, they can contact one of the health professionals advice lines listed here.

Contacts for Healthcare Professionals

Scotland: Public Health Scotland Travel Health Advice Line Telephone: 0141 300 1130

England, Wales and Northern Ireland: Travel Health NaTHNaC Advice Line Telephone: 020 7383 7474


TRAVAX Yellow Fever Disease Page

TRAVAX Yellow Fever FAQ Page

fitfortravel Yellow Fever Vaccine page

Yellow fever: the green book, chapter 35

Yellow Fever Vaccination Centres Information Pack

Report of the Commission on Human Medicine’s Expert Working Group on benefit-risk and risk minimisation measures of the yellow fever vaccine (2019)

Yellow Fever Vaccine eLearning Resource